GO:0032281 cellular_component AMPA glutamate receptor complex
| PAG Title | GO:0032281 cellular_component AMPA glutamate receptor complex |
| PAG ID | TAX021434 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 1,525 |
| Information Content | Rich |
| Other IDs | GO:0032281 |
| Base PAG ID | TAX021434 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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